ISSN 1662-4009 (online)

ey0016.10-4 | (1) | ESPEYB16

10.4. Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study

Rawshani Araz , Sattar Naveed , Franzen Stefan , Rawshani Aidin , Hattersley Andrew T , Svensson Ann-Marie , Eliasson Bjorn , Gudbjornsdottir Soffia

To read the full abstract: Lancet 218; 392: 451–530Despite great improvements in diabetes care, people with type 1 diabetes (T1D) remain at increased risk of mortality and morbidity, in particular from cardiovascular disease (CVD). How exactly diabetes leads to CVD and which factors contribute to the increased risk profile is still largely unknown. Molecular mechanisms are being stu...

ey0016.10-17 | (1) | ESPEYB16

10.17. Relative prognostic importance and optimal levels of risk factors for mortality and cardiovascular outcomes in type 1 diabetes mellitus

A Rawshani , A Rawshani , N Sattar , S Franzen , DK McGuire , B Eliasson , AM Svensson , B Zethelius , M Miftaraj , A Rosengren , S Gudbjornsdottir

To read the full abstract: Circulation. 2019;139:1900–1912Numerous publications have reported that higher HbA1c levels relate to higher cardiovascular disease (CVD) risk in people with type 1 diabetes (T1D). However, the strength of association and optimal HbA1c levels are not established.This analysis of T1D patients recorded in the Swedish National Diabetes ...

ey0016.10-16 | (1) | ESPEYB16

10.16. BMI, mortality, and cardiovascular outcomes in type 1 diabetes: Findings against an obesity paradox

J Edqvist , A Rawshani , M Adiels , L Bjorck , M Lind , AM Svensson , S Gudbjornsdottir , N Sattar , A Rosengren

To read the full abstract: Diabetes Care. 2019;42:1297–1304In normal populations, high BMI is associated with higher mortality and morbidity, in particular from cardiovascular disease (CVD). In contrast, in type 1 diabetes (T1D), low body weight has been associated with increased mortality risks. This study investigated the importance of weight and weight gain/loss in patients with ...